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Herpes expert H. Hunter Handsfield, MD explains the basics about genital herpes, including the difference between genital HSV-1 and HSV-2 infection, testing options and the importance of knowing virus type, and the three-prong strategy for prevention. See more herpes videos at sexualhealthTV. Handsfield or our other experts to answer? Visit our Ask the Experts page to learn how.

Etiology, transmission and protection: Herpes simplex virus-2 HSV-2 is a leading cause of sexually transmitted infections with recurring manifestations throughout the lifetime of infected hosts. Currently no effective vaccines or prophylactics exist that provide complete protection or immunity from the virus, which is endemic throughout the world. Immunocompromised patients including neonates are susceptible to additional systemic infections including debilitating consequences of nervous system inflammation. Epidemiology, incidence and prevalence: More than million people are infected worldwide and most reported cases involve the age groups between years, which coincides with an increase in sexual activity among this age group. While these numbers are an estimate, the actual numbers may be underestimated as many people are asymptomatic or do not report the symptoms. Treatment and curability: Currently prescribed medications, mostly nucleoside analogs, only reduce the symptoms caused by an active infection, but do not eliminate the virus or reduce latency.

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Metrics details. Herpes simplex virus types 1 and 2 HSV1 and HSV2 are infectious agents, and their association with cancer occurrence in human is a controversial topic for decades. Eight data cycles —, —, —, —, —, —, —, and — were employed, and a sample of female participants was used in this study according to the availability of cancer history and HSV serostatus.