Cancer cancerous fiber mature muscle

Supplementary information and source data files are available in the online version of the paper or can be obtained from corresponding author upon request. The uncropped immunoblot images used in the main figures are shown in Supplementary Fig. De-identified patient information with relevant clinical annotation are available in the Supplementary Table , Life Sciences Reporting Summary. Additional de-identified data with clinical annotation are available upon reasonable request from the corresponding author. Metastatic cancer patients experience a severe loss of skeletal muscle mass and function known as cachexia. Cachexia is associated with poor prognosis and accelerated death in cancer patients, yet its underlying mechanisms remain poorly understood.

Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer, and can spread to other areas of the body. To learn more about how cancers start and spread, see What Is Cancer? For information about the differences between childhood cancers and adult cancers, see Cancer in Children.

This page is about the different types of cancer according to the type of cell they start from. You can read about. They are very similar but vary in some ways because body organs do very different things. For example, nerves and muscles do different things, so the cells have different structures. We can also classify cancers according to where they start in the body, such as breast cancer or lung cancer.

The soft tissues of the body include the muscles, tendons bands of fiber that connect muscles to bones , fat, blood vessels , lymph vessels , nerves , and tissues around joints. Adult soft tissue sarcomas can form almost anywhere in the body, but are most common in the head, neck, arms, legs, trunk , abdomen , and retroperitoneum. Enlarge Soft tissue sarcoma forms in soft tissues of the body, including muscle, tendons, fat, blood vessels, lymph vessels, nerves, and tissue around joints. There are many types of soft tissue sarcoma. The cells of each type of sarcoma look different under a microscope , based on the type of soft tissue in which the cancer began.